@thesis{thesis,
		author={HANDINI  Ellyana Nur},
		title ={Formulasi Gel Ekstrak Metanol Terfurifikasi Tanaman Api-Api (Avicennia Marina) dengan Gelling Agent CMC},
		year={2021},
		url={http://repository.unsoed.ac.id/11003/},
		abstract={Api-api (Avicennia marina) leaves contain secondary metabolites such as flavonoid, tannin, saponin, terpenoid, and alkaloid play a role in the healing process of burns. This study was aimed to determine the effect of variations of gelling agent CMC concentration on physical properties and the stability of Api-api leaves methanol extract purified gel.
Methods: This study is experimental researches includes extraction and purification of Api-api leaves, formulation of gel preparations, and evaluation of physical properties and gel stability. The gels were prepared with a variation of CMC concentration of 2%, 3%, 4%, and 5%. Each gel was evaluated for physical properties and the stability for 28 days. The results of the physical evaluation and gel preparations were analyzed using Graphpad Prism.
Results: Variations in CMC concentration in Api-api leaves purified methanol extract gel can increase viscosity and adhesion, decrease dispersion, and stable in freeze-thaw stability. This is due to the presence of propylene glycol as a humectant which easily binds water from the air and increases the volume of water in the gel.

Conclusion: Api-api leaves purified methanol extract gel that meets the requirement is Formula IV with 5% CMC concentration.

Keywords: Avicennia marina, Gelling agent, CMC, Gel}
		}