Abstract :
Background: The Indonesian Cancer Foundation (YKI) noted that from population
data in Lampung in 2020 there were around 5.672 cancer patients. Meanwhile, the
largest numbers are breast cancer and cervical cancer. This study aims to determine
the relationship between stage and treatment with the degree of anemia in cervical
cancer patients.
Metodhs: This research uses an observational analytical method with a crosssectional
approach.
The
sample
consisted
of
172
medical
records
of
cervical
cancer
patients
at
Abdul
Moeloek
Hospital
Bandar
Lampung
using
consecutive
sampling
technique.
Statistical analysis was carried out using univariate analysis, bivariate
analysis using the chi-square method and multivariate analysis using the multiple
logistic regression method.
Results: Based on the research findings, the majority of respondents were
diagnosed in the early stage (52,9%). The types of treatment undergone by the
respondents consisted of chemotherapy (26,2%), radiotherapy (29,7%), surgery
(22,7%), and combination therapy (21,5%). Variables associated with the degree of
anemia in cervical cancer patients (?<0,05) were stage, chemotherapy, radiotherapy
(p value<0,001), surgery (p value=0,001), combination therapy (p value=0,021)
The results of multivariate analysis indicated that chemotherapy and radiotherapy
were statistically significant, with p values of <0,001 each.
Conclusion: Stage, chemotherapy, radiotherapy, surgery, and combination therapy
are associated with the degree of anemia in cervical cancer patients. The most
significant relationships with the degree of anemia are found with the chemotherapy
and radiotherapy.
Keywords: Cervical cancer, chemotherapy, degree of anemia, radiotherapy, stage
Latar Belakang: Yayasan Kanker Indonesia (YKI) mencatat dari data penduduk
di Lampung pada 2020 ada sekitar 5.672 pasien kanker. Sementara jumlah
terbanyak yakni kanker payudara dan kanker serviks. Penelitian ini bertujuan untuk
mengetahui hubungan stadium dan pemberian tindakan dengan derajat anemia
pasien kanker serviks.
Metode: Penelitian ini menggunakan metode analitik observational dengan
pendekatan crossectional. Sampel berjumlah 172 rekam medis pasien kanker
serviks di RSUD Abdul Moeloek Bandar Lampung dengan teknik pengambilan
consecutive sampling. Analisis statistik dilakukan dengan analisis univariat,
bivariat dengan metode chi-square dan multivariat dengan metode regresi logistik
berganda.
Hasil: Berdasarkan hasil penelitian, sebagian besar responden terdiagnosa stadium
awal (52,9%). Jenis tindakan yang dijalani oleh responden terdiri atas kemoterapi
(26,2%), radioterapi (29,7%), pembedahan (22,7%), tindakan kombinasi (21,5%).
Variabel yang berhubungan dengan derajat anemia pada pasien kanker serviks
(?<0,05), yaitu stadium, kemoterapi, radioterapi (p value<0,001), pembedahan (p
value=0,001), tindakan kombinasi (p value=0,021). Hasil analisis multivariat
kemoterapi dan radoterapi bermakna secara statistik didapatkan masing-masing (p
value<0,001).
Simpulan: Stadium, kemoterapi, radioterapi, pembedahan, dan tindakan kombinasi
berhubungan dengan derajat anemia pasien kanker serviks. Hubungan yang paling
signifikan dengan derajat anemia adalah kemoterapi dan radioterapi.
Kata Kunci: derajat anemia, kanker serviks, kemoterapi, radioterapi, stadium