PROFIL KLINIS PENGGUNAAN OBAT ANTI DIABETES MELITUS TIPE II DI RUMAH SAKIT ABUNAWAS KENDARI SULAWESI TENGGARA
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Institusion
Universitas Muslim Indonesia
Author
Herman, Hendra
Subject
R Medicine (General)
Datestamp
2025-08-20 04:58:34
Abstract :
ABSTRACT ANDI SYAMSINAR. Clinical Profile of Use of Type II Anti-Diabetes Mellitus Drugs at Abunawas Kendari Hospital, Southeast Sulawesi (Supervised by Andi Maulana and Hendra Herman). Diabetes Mellitus (DM) is a condition in which blood sugar levels are higher than normal. This study aims to see the clinical profile of antidiabetic drug use in type 2 DM patients based on laboratory examinations regarding the type of drug, dose of drug, and duration of antidiabetic drug administration at Abunawas Hospital, Kendari, Southeast Sulawesi. This study design uses a descriptive research type with a retrospective data collection method based on medical records with a sample size of 36 type 2 Diabetes Mellitus patients and using the Multivariate method. The results of the study showed that the patients who mostly suffered from type 2 Diabetes Mellitus were women with an age range of 60 years. The most effective and most widely used oral antidiabetic use is single therapy of the biguanide group Metformin 500 mg and the results of statistical analysis using the Multivariat method where the results obtained were at the p-value of Metformin, which was 1.0 where > 0.05 which means that there is no significant difference between metformin and other types of single therapy drugs or combination therapy. Meanwhile, the p-value of Glimepiride is 0.048, Sitagliptin is 0.011, and combination therapy (Metformin + Glimepiride) is 0.029 where <0.05. The conclusion of this study is that the most effective use of antidiabetic is Metformin and there is a significant relationship between the use of oral antidiabetic with blood sugar and HbA1c examinations. Keywords: Oral Antidiabetic, Diabetes Mellitus, Usage Pattern, Effectiveness..
ABSTRACT ANDI SYAMSINAR. Clinical Profile of Use of Type II Anti-Diabetes Mellitus Drugs at Abunawas Kendari Hospital, Southeast Sulawesi (Supervised by Andi Maulana and Hendra Herman). Diabetes Mellitus (DM) is a condition in which blood sugar levels are higher than normal. This study aims to see the clinical profile of antidiabetic drug use in type 2 DM patients based on laboratory examinations regarding the type of drug, dose of drug, and duration of antidiabetic drug administration at Abunawas Hospital, Kendari, Southeast Sulawesi. This study design uses a descriptive research type with a retrospective data collection method based on medical records with a sample size of 36 type 2 Diabetes Mellitus patients and using the Multivariate method. The results of the study showed that the patients who mostly suffered from type 2 Diabetes Mellitus were women with an age range of 60 years. The most effective and most widely used oral antidiabetic use is single therapy of the biguanide group Metformin 500 mg and the results of statistical analysis using the Multivariat method where the results obtained were at the p-value of Metformin, which was 1.0 where > 0.05 which means that there is no significant difference between metformin and other types of single therapy drugs or combination therapy. Meanwhile, the p-value of Glimepiride is 0.048, Sitagliptin is 0.011, and combination therapy (Metformin + Glimepiride) is 0.029 where <0.05. The conclusion of this study is that the most effective use of antidiabetic is Metformin and there is a significant relationship between the use of oral antidiabetic with blood sugar and HbA1c examinations. Keywords: Oral Antidiabetic, Diabetes Mellitus, Usage Pattern, Effectiveness..
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