Formulasi dan Evaluasi Sabun Padat Transparant Ekstrak Frezzed Drying Kayu Secang (Caesalpinia Sappan L) Sebagai Sabun Anti Jerawat
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Institusion
Poltekkes Kemenkes Tanjung Karang
Author
Yulyuswarni, Yulyuswarni
Mulatasih, Endah Ratna Sari
Mulatasih, Endah Ratna Sari
Subject
RS Pharmacy and materia medica
Datestamp
2021-10-21 07:43:46
Abstract :
Acne (acne vulgaris) is an abnormal condition of the skin due to the production of excess oil glands that cause clogging of skin pores. Acne develops into inflammation (inflammatory acne) when infected with bacteria, especially the Propionibacterium acnes bacteria. Secang wood extract (Caesalpinia sappan L) contains Brazilin flavonoids which are known to have inhibitory properties against the Propionibacterium acne bacteria. One of the acne treatments is using acne soap. Therefore, this study aims to obtain a transparent soap preparation formula with the active ingredient of Secang wood extract (Caesalpinia sappan L), formulation techniques and to determine the antibacterial activity against P. acne bacteria that causes acne. So it is hoped that Secang wood can be developed into a medicinal cosmetic product, which has economic value. The colour of transparent soap is light purple to dark purple red, with a solid texture and a distinctive VCO aroma, has a pH of 9.3-9.7. The levels of free fatty acids / free alkalis are 0.04-0.4% , unsweetened fats 0.29-0.34% , have a water content of 18% -30.6% , have total fat content 15.96% -30.98% . The inhibitory diameter of transparent solid soap F4 = 24.50 mm was greater than F0 = 21.67 mm but it was not significantly different Keywords: Transparent soap, Sappan wood, Freez drying
Acne (acne vulgaris) is an abnormal condition of the skin due to the production of excess oil glands that cause clogging of skin pores. Acne develops into inflammation (inflammatory acne) when infected with bacteria, especially the Propionibacterium acnes bacteria. Secang wood extract (Caesalpinia sappan L) contains Brazilin flavonoids which are known to have inhibitory properties against the Propionibacterium acne bacteria. One of the acne treatments is using acne soap. Therefore, this study aims to obtain a transparent soap preparation formula with the active ingredient of Secang wood extract (Caesalpinia sappan L), formulation techniques and to determine the antibacterial activity against P. acne bacteria that causes acne. So it is hoped that Secang wood can be developed into a medicinal cosmetic product, which has economic value. The colour of transparent soap is light purple to dark purple red, with a solid texture and a distinctive VCO aroma, has a pH of 9.3-9.7. The levels of free fatty acids / free alkalis are 0.04-0.4% , unsweetened fats 0.29-0.34% , have a water content of 18% -30.6% , have total fat content 15.96% -30.98% . The inhibitory diameter of transparent solid soap F4 = 24.50 mm was greater than F0 = 21.67 mm but it was not significantly different Keywords: Transparent soap, Sappan wood, Freez drying
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